Short-term ubiquinol-10 supplementation alleviates tissue damage in muscle and fatigue caused by strenuous exercise in male distance runners. 49 Plasma levels reached 8 mg/L with a dose of 2400 mg/d but did not increase with doses of 3000 mg/d. Suzuki Y, Nagato S, Sakuraba K, Morio K, Sawaki K. Among non-HF studies, CoQ10 doses of 3000 mg/d have been used in Parkinson patients. CoQ10 supplementation in patients undergoing IVF-ET: the relationship with follicular fluid content and oocyte maturity. Giannubilo S, Orlando P, Silvestri S, et al. Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects. Effectiveness of coenzyme q10 supplementation for type 2 diabetes mellitus: a systematic review and meta-analysis. Coenzyme Q10 supplementation decreases statin-related mild-to-moderate muscle symptoms: a randomized clinical study. Skarlovnik A, Janić M, Lunder M, Turk M, Šabovič M. Coenzyme Q10 supplementation: efficacy, safety, and formulation challenges. Coenzyme q10 supplementation in aging and disease. Hernández-Camacho JD, Bernier M, López-Lluch G, Navas P. doi:10.1161/JAHA.118.009835īarcelos IP de, Haas RH. Coenzyme Q10 (CoQ10) is not FDA-approved to treat any medical condition, although it is widely available over-the-counter as a dietary supplement and recommended by primary care providers and specialists alike. Effects of coenzyme q10 on statin‐induced myopathy: an updated meta‐analysis of randomized controlled trials. Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-a meta-analysis. Sazali S, Badrin S, Norhayati MN, Idris NS. Effectiveness of coenzyme Q10 supplementation for type 2 diabetes mellitus: a systematic review and meta-analysis. Zhang SY, Yang KL, Zeng LT, Wu XH, Huang HY. Effects of coenzyme Q10 supplementation on glycemic control: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Coenzyme q10, ageing and the nervous system: an overview. The effects of coenzyme q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. Coenzyme Q10 in cardiovascular and metabolic diseases: current state of the problem. Zozina Vl, Covantev S, Goroshko OA, et al. The two biggest RCTs saw beneficial effects at a dosage of 120 mg per day for 2448 weeks, suggesting that (to see significant benefits) supplementation should last at least 6 months. Coenzyme Q10 in the treatment of heart failure: a systematic review of systematic reviews. Whilst results are contradictory, the overall evidence suggests that CoQ10 may be beneficial in terms of improving blood lipids. Jafari M, Mousavi SM, Asgharzadeh A, Yazdani N. Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with coronary artery disease. National Center for Complementary and Integrative Health.
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